TUOLUMNE COUNTY, CA - The 2012 Amgen Tour of California makes its only swing through the Sierra foothills when participants race 130 miles from Sonora to Clovis Wednesday.

PHOTOS: 2012 Amgen Tour of California Stage 1 & 2 Highlights

Expect the following road closures. The times are approximate.

· Highway 49 will be closed for northbound traffic from Highway-120 beginning at 10 a.m. to 11:30 a.m. Roadway will be closed to southbound traffic beginning 30 minutes prior to the arrival of the race.

· Highway 49 will be closed for northbound traffic from County Road 152 beginning at 10:30 a.m. to 12:45 p.m. Roadway will be closed to southbound traffic beginning 30 minutes prior to the arrival of the race.

STOCKTON, CA - The San Joaquin County District Attorney's Office has charged a man with refusing to follow health orders after allegedly not taking medication for his tuberculosis.

Armando Rodriguez, 34, is now behind bars at the county jail until he's considered healthy enough to be near others.

Prosecutor Stephen Taylor said Rodriguez was arrestable after not being home to meet with health officials who would bring the medication and make sure the patient takes it.

Taylor said cases like this happen once or twice a year in San Joaquin County and it's usually for the same reason. 

"Narcotics. The TB meds don't work with street drugs at all, " Taylor said. "They neutralize opiates, so if you're a heroin addict, you can't get high. So you make choices. It's a matter of priorities."

HONOLULU (AP) -- An airline that connects small cities with leisure destinations is adding four mainland cities to its Hawaii service.

Starting in November, Allegiant Air will offer nonstop flights between Honolulu and Bellingham, Wash., Eugene, Ore., Santa Maria, Calif., and Stockton, Calif. The carrier will also offer nonstop flights between Maui and Bellingham.

Introductory one-way fares as low as $159 are being offered, which must be purchased by May 21 for travel by Jan. 15.

Tuesday's announcement comes after Las Vegas-based Allegiant Travel Co. previously announced flights to Las Vegas and Fresno will begin in June.